Recent Publications

Bühler MM, Lu J, Scheinost S, Nadeu F, Roos-Weil D, Hensel M, Thavayogarajah T, Moch H, Manz MG, Haralambieva E, Marques Maggio E, Beà S, Giné E, Campo E, Bernard OA, Huber W, Zenz TSAMHD1 mutations in mantle cell lymphoma are recurrent and confer in vitro resistance to nucleoside analoguesLeuk Res. 2021 May 3;107:106608. doi: 10.1016/j.leukres.2021.106608

Grever M, Andritsos L, Banerji V, Barrientos JC, Bhat S, Blachly JS, Call T, Cross M, Dearden C, Demeter J, Dietrich S, Falini B, Forconi F, Gladstone DE, Gozzetti A, Iyengar S, Johnston JB, Juliusson G, Kraut E, Kreitman RJ, Lauria F, Lozanski G, Parikh SA, Park J, Polliack A, Ravandi F, Robak T, Rogers KA, Saven A, Seymour JF, Tadmor T, Tallman MS, Tam CS, Tiacci E, Troussard X, Zent C, Zenz T, Zinzani PL, Wörmann B. Hairy cell leukemia and COVID-19 adaptation of treatment guidelines. Leukemia 2021 May 4:1-9. doi: 10.1038/s41375-021-01257-7

Alankus B, Ecker V, Vahl N, Braun M, Weichert W, Macher-Göppinger S, Gehring T, Neumayer T, Zenz T, Buchner M, Ruland J. Pathological RANK signaling in B cells drives autoimmunity and chronic lymphocytic leukemia. J Exp Med. 2021 Feb 1;218(2):e20200517. doi: 10.1084/jem.20200517

 

Nadeu F, Royo R, Clot G, Duran-Ferrer M, Navarro A, Martin S, Lu J, Zenz T, Baumann TS, Jares P, Puente XS, Martin-Subero I, Delgado J, Campo E. IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics. Blood. 2020 Nov 19:blood.2020008311. doi: 10.1182/blood.2020008311

Nadeu F, Mas-de-Les-Valls R, Navarro A, Royo R, Martín S, Villamor N, Suárez-Cisneros H, Mares R, Lu J, Enjuanes A, Rivas-Delgado A, Aymerich M, Baumann T, Colomer D, Delgado J, Morin RD, Zenz T, Puente XS, Campbell PJ, Beà S, Maura F, Campo E. IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms. Nat Commun.2020 Jul 7;11(1):3390. doi:10.1038/s41467-020-17095-7

 

Preprints

Almut Lütge, Junyan Lu, Jennifer Hüllein, Tatjana Walther, Leopold Sellner, Bian Wu, Richard Rosenquist, Christopher C. Oakes, Sascha Dietrich, Wolfgang Huber, Thorsten Zenz. Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia

bioRxiv 2021.04.16.440134; doi: https://doi.org/10.1101/2021.04.16.440134

Marco M. Bühler, Junyan Lu, Sebastian Scheinost, Ferran Nadeu, Damien Roos-Weil, Manfred Hensel, Tharshika Thavayogarajah, Holger Moch, Markus G. Manz, Eugenia Haralambieva, Ewerton Marques Maggio, Sílvia Beà, Eva Giné, Elías Campo, Olivier A. Bernard, Wolfgang Huber, Thorsten Zenz SAMHD1 mutations in mantle cell lymphoma: disease driver conferring in vitro resistance to nucleoside analogues

bioRxiv 2020.06.09.140376; doi: https://doi.org/10.1101/2020.06.09.140376

Justyna A. Wierzbinska, Reka Toth, Naveed Ishaque, Karsten Rippe, Jan-Philipp Mallm, Lara Klett, Daniel Mertens, Thorsten Zenz, Thomas Hielscher, Marc Seifert, Ralf Küppers, Yassen Assenov, Pavlo Lutsik, Stephan Stilgenbauer, Philipp M. Roessner, Martina Seiffert, John Byrd, Christopher C. Oakes, Christoph Plass, Daniel B. Lipka. Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

bioRxiv 2020.02.04.933937; doi: https://doi.org/10.1101/2020.02.04.933937